Blar i Bergen Open Research Archive på forfatter "Soiland, Havard"
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Effect of genetic variability in 20 pharmacogenes on concentrations of tamoxifen and its metabolites
Chen, Yuanhuang; Marcath, Lauren A.; Eliassen, Finn Magnus; Lende, Tone Hoel; Soiland, Havard; Mellgren, Gunnar; Helland, Thomas; Hertz, Daniel Louis (Journal article; Peer reviewed, 2021)Background: Tamoxifen, as a treatment of estrogen receptor positive (ER+) breast cancer, is a weak anti-estrogen that requires metabolic activation to form metabolites with higher anti-estrogenic activity. Endoxifen is the ...